Figures
Human macrophages infected by Leishmania donovani
Human macrophages derived from THP1 monocytes are infected by Leishmania donovani parasites. The parasites are genetically engineered to express green fluorescent protein (in green). Nuclei of the host cells are stained with DAPI (in red). Images are obtained by confocal fluorescence microscopy at dual excitation/emission channels and superimposed. Automated image analysis renders parasite and macrophage cells counts, as well as number of infected cells, in the absence and presence of drug treatment. Tegazzini D et al.
Image Credit: Imanol Peña-Urquiza
Citation: (2017) PLoS Neglected Tropical Diseases Issue Image | Vol. 11(6) June 2017. PLoS Negl Trop Dis 11(6): ev11.i06. https://doi.org/10.1371/image.pntd.v11.i06
Published: June 30, 2017
Copyright: © 2017 Peña-Urquiza. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Human macrophages derived from THP1 monocytes are infected by Leishmania donovani parasites. The parasites are genetically engineered to express green fluorescent protein (in green). Nuclei of the host cells are stained with DAPI (in red). Images are obtained by confocal fluorescence microscopy at dual excitation/emission channels and superimposed. Automated image analysis renders parasite and macrophage cells counts, as well as number of infected cells, in the absence and presence of drug treatment. Tegazzini D et al.
Image Credit: Imanol Peña-Urquiza