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PLoS Pathogens Issue Image | Vol. 10(5) May 2014

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Pseudo-atomic model of complete rotavirus uncleaved spike.

The structure is derived from the analysis by cryo-electron microscopy and cryo-electron tomography of non-trypsinized virions from two rotavirus model strains. The undigested spike is able to achieve a stable, rigid conformation similar to that of the mature trypsin-cleaved particle. See Rodríguez et al.

Image Credit: Javier M. Rodríguez, Francisco J. Chichón, Esther Martín-Forero, Fernando González-Camacho, José L. Carrascosa, José R. Castón and Daniel Luque (CNM/ISCIII and CNB/CSIC, Spain)

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Pseudo-atomic model of complete rotavirus uncleaved spike.

The structure is derived from the analysis by cryo-electron microscopy and cryo-electron tomography of non-trypsinized virions from two rotavirus model strains. The undigested spike is able to achieve a stable, rigid conformation similar to that of the mature trypsin-cleaved particle. See Rodríguez et al.

Image Credit: Javier M. Rodríguez, Francisco J. Chichón, Esther Martín-Forero, Fernando González-Camacho, José L. Carrascosa, José R. Castón and Daniel Luque (CNM/ISCIII and CNB/CSIC, Spain)

https://doi.org/10.1371/image.ppat.v10.i05.g001