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Genome-Scale Reconstruction and Analysis of the Pseudomonas putida KT2440 Metabolic Network Facilitates Applications in Biotechnology

Figure 6

Mutational strategies for increased PHA production.

This figure highlights 6 strategies suggested by the modified optknock approach for increased production of AcCoA, a precursor for polyhydroxyalkanoates. (A) AcCoA production ranges vs. growth yield of in silico strains developed using the ‘AcCoA production’ strategy. (B) AcCoA pooling versus growth yield of in silico strains developed using the ‘AcCoA pooling’ strategy.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1000210.g006