Sepsid even-skipped Enhancers Are Functionally Conserved in Drosophila Despite Lack of Sequence Conservation
Figure 2
Conservation within and between sepsids and Drosophila.
The eve locus (20 kb flanking the eve protein-coding gene) is shown for two Drosophila (D. melanogaster and D. virilis) and two sepsid species (S. cynipsea and T. putris), centered on the eve homeodomain. Black lines represent significant BLASTZ [15] hits on the plus strand, red lines on the minus strand (BLASTZ parameters: K = 1800, with chaining). Verified D. melanogaster enhancers are shown in green and predicted sepsid enhancers in black. Note that only a subset of D. melanogaster eve enhancers are shown here; all BLASTZ matches between D. melanogaster and S. cynipsea fall within known enhancers with the exception of those falling within 500 bp of the transcription start site in D. melanogaster.