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Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

Figure 5

ORI specification and firing efficiency across cell types.

Relative abundance of 9 CpG island-ORI regions and 10 non promoter-ORI regions in 300–800 nt long nascent strands derived from ES cells, MEFs and NIH/3T3 fibroblasts. Averaged values for the non-ORI regions were considered as baseline in each cell type.

Figure 5

doi: https://doi.org/10.1371/journal.pgen.1000446.g005