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Breast Cancer DNA Methylation Profiles Are Associated with Tumor Size and Alcohol and Folate Intake

Figure 1

Unsupervised clustering heatmap of CpG methylation in breast carcinomas.

Unsupervised hierarchical clustering heat map based on Manhattan distance and average linkage of the 750 autosomal CpG loci with the highest variance. Samples are in rows (n = 162), and CpG loci are in columns. Blue indicates methylated and yellow indicates unmethylated.

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1001043.g001