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Breast Cancer DNA Methylation Profiles Are Associated with Tumor Size and Alcohol and Folate Intake

Figure 3

Recursively partitioned mixture model of CpG methylation in breast carcinomas.

The figure depicts the results of RPMM. Columns represent CpG sites and rows represent methylation classes. The height of each row is proportional to the number of observations residing in the class, total n = 162. Blue indicates methylated and yellow indicates unmethylated. Methylation classes are numbered one through eight on the left. The color of the columns within each class represents the average methylation of the CpG for that class.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1001043.g003