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Correction: Recurrent Evolution of Melanism in South American Felids

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Due to an error in the production process, the labels for panel D in Fig. 1 are misaligned. The correct figure is provided here.

The Dryad DOI in the Data Availability Statement links out incorrectly. The correct Dryad link is http://dx.doi.org/10.5061/dryad.pq482.

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Fig 1. Melanism mutations and phenotypes in three Leopardus species.

(A) Color phenotypes of the pampas cat (L. colocolo), Geoffroy’s cat (L. geoffroyi), and kodkod (L. guigna). Tabby markings in the non-melanistic (NM) forms shown here are obscured in the melanistic (M) forms. (B) Geographic distribution (modified from [7]); red circles represent the approximate origin of samples as described in the text. Right upper panel indicates phylogenetic relationships and estimated divergence times based on [4] (C, D) Location of missense variants in ASIP (kodkod, pampas cat) and MC1R (Geoffroy’s cat). (C) The kodkod and pampas cat variants are predicted to disrupt the three dimensional structure of a disulfide-stabilized loop in ASIP that is critical for MC1R binding [30]. (D) The Geoffroy’s cat melanism allele carries three missense variants in MC1R; C125R is likely to be causative as described in the text.

https://doi.org/10.1371/journal.pgen.1005126.g001

Reference

  1. 1. Schneider A, Henegar C, Day K, Absher D, Napolitano C, et al. (2015) Recurrent Evolution of Melanism in South American Felids. PLoS Genet 11(2): e1004892. pmid:25695801