SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
Figure 10
CR had no beneficial effect on survival of SirT1-null mice.
Survival curve for normal (A) and SirT1-null (B) mice that were fed the CR of AL diets. Mutant mice that were euthanized because of eyelid inflammation were excluded from this graph. Grey rectangles represent the period when CR started (5 to 7 months old).