Inhibition of Iron Uptake Is Responsible for Differential Sensitivity to V-ATPase Inhibitors in Several Cancer Cell Lines
Figure 10
Ferroportin expression in SK-Mel-5 cells is decreased by the antioxidant NAC.
SK-Mel-5 cells were treated with NAC as described in the Methods and then processed for immunoblotting with antibodies against the proteins shown. TfR, transferrin receptor. FPN1, ferroportin 1. FTH, ferritin H heavy chain. The immunoblots shown are representative of two independent experiments.