Computational Analysis of HIV-1 Resistance Based on Gene Expression Profiles and the Virus-Host Interaction Network
Figure 2
The IFS curve for HIV-1-resistant and susceptible sample classification.
In the IFS curve, the x-axis is the number of genes used for classification, and the y-axis is the prediction accuracies of nearest neighbor algorithm evaluated by Leave-One-Out Cross-Validation (LOOCV). The peak accuracy was 0.852 with 185 genes. The top 185 genes in the mRMR gene list formed the optimal discriminative gene set.