TANGLE: Two-Level Support Vector Regression Approach for Protein Backbone Torsion Angle Prediction from Primary Sequences
Figure 7
The predicted and observed torsion angles for three typical alpha-, beta-, and alpha/beta-proteins.
The three proteins are: (A) the beta1-subunit of the signal-transducing G protein heterotrimer (PDB: 1b9x, chain A) [85]; (B) the enzyme IIAlactose from Lactococcus lactis (PDB: 1e2a, chain A) [86] and (C) the bee venom hyaluronidase (PDB: 1fcv, chain: A) [87]. Secondary structure annotations of these proteins by DSSP [40] are shown at the bottom of each panel, with alpha-helix, beta-strand and coil residues represented by red curves, yellow arrows and black lines, respectively. The observed and predicted torsion angle values are represented by blue-solid and red-dashed lines, respectively.