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Medullospheres from DAOY, UW228 and ONS-76 Cells: Increased Stem Cell Population and Proteomic Modifications

Figure 8

The physical interactions network.

Protein-protein interaction are identify by pink edges. The black nodes, white edged represent the physical interactions of the common proteins differentially expressed in all DAOY, UW228 and ONS-76 adherent and sphere cell lines, while Sp overexpressed proteins are yellow edged and specific cell type DAOY(A), UW228 (B) and ONS-76 (C) Sp/Ads are green, blue and pink edged respectively. Grey proteins represented new interactions identified in Genemania proteomic databases. The edge width correspond to the weight of interaction.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0063748.g008