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Sparstolonin B Inhibits Pro-Angiogenic Functions and Blocks Cell Cycle Progression in Endothelial Cells

Figure 4

SsnB inhibits ex vivo angiogenesis in the CAM assay.

A. 100 µM SsnB decreased normalized total blood vessel length. B. 100 µM SsnB decreased normalized branching number. *p<0.05 vs. vehicle control, Newman-Keuls test. C. Representative micrographs demonstrating blood vessels in the CAM assay (left – vehicle control, right – 100 µM SsnB, circles show approximate position of methylcellulose discs).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0070500.g004