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The BTB-Containing Protein Kctd15 Is SUMOylated In Vivo

Figure 5

Kctd15 conjugated to SUMO1 is less competent in inhibiting AP-2α activity and NC formation.

(A) Diagram of the fusion protein between Kctd15 and SUMO1. (B) Kctd15-SUMO1 conjugated protein was less effective than WT in repressing AP-2α dependent reporter activation. (C) Injection into zebrafish embryos of Kctd15-SUMO1 failed to abolish NC formation.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0075016.g005