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Brain Deactivation in the Outperformance in Bimodal Tasks: An fMRI Study

Figure 2

Schematic results of the statistical parametric mapping (SPM) analysis of the contrasts.

An uncorrected threshold of p = 0.001 was used for the voxel illustration. The SPM results were superimposed onto the SPM toolbox, xjView, with a template of brain structure indexed for the coordinate of the z axis according to the MNI space. Unimodal stimuli versus rests were indicated in yellow and red words for visual and auditory activation, respectively (FWE p< 0.05).Brain regions activated by visual and auditory stimuli, selected with FWE p value between 0.05 and 0.08, were in cyan and purple words, respectively, and were also depicted in yellow and red colors in the corresponding brain areas. A mask was formed to examine the bimodal task versus the average of unimodal tasks. The results shown in the green words and circles indicate three activated areas including the medial parietal lobe, BA9 and BA6, all outside the mask (FWE p value < 0.05). Finally, fifteen areas formed a ROI to examine the performance of subjects that outperformed bimodal tasks versus those who performed well in only one of the bimodal tasks. The ROI analysis shown in white circles revealed that the medial frontal lobe, FEF, BA6, BA7, and medial parietal lobe were negatively correlated with the contrast (t test, p < 0.05).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0077408.g002