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Are Reports of Psychological Stress Higher in Occupational Studies? A Systematic Review across Occupational and Population Based Studies

  • Laura Goodwin ,

    laura.goodwin@kcl.ac.uk

    Affiliation King's Centre for Military Health Research, Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, United Kingdom

  • Ilan Ben-Zion,

    Affiliation King's Centre for Military Health Research, Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, United Kingdom

  • Nicola T. Fear,

    Affiliation King's Centre for Military Health Research, Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, United Kingdom

  • Matthew Hotopf,

    Affiliation Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, United Kingdom

  • Stephen A. Stansfeld,

    Affiliation Centre for Psychiatry, Queen Mary University of London, Barts and The London, London, United Kingdom

  • Simon Wessely

    Affiliation King's Centre for Military Health Research, Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, United Kingdom

Abstract

Objectives

The general health questionnaire (GHQ) is commonly used to assess symptoms of common mental disorder (CMD). Prevalence estimates for CMD caseness from UK population studies are thought to be in the range of 14–17%, and the UK occupational studies of which we are aware indicate a higher prevalence. This review will synthesise the existing research using the GHQ from both population and occupational studies and will compare the weighted prevalence estimates between them.

Methods

We conducted a systematic review and meta-analysis to examine the prevalence of CMD, as assessed by the GHQ, in all UK occupational and population studies conducted from 1990 onwards.

Results

The search revealed 65 occupational papers which met the search criteria and 15 relevant papers for UK population studies. The weighted prevalence estimate for CMD across all occupational studies which used the same version and cut-off for the GHQ was 29.6% (95% confidence intervals (CIs) 27.3–31.9%) and for comparable population studies was significantly lower at 19.1% (95% CIs 17.3–20.8%). This difference was reduced after restricting the studies by response rate and sampling method (23.9% (95% CIs 20.5%–27.4%) vs. 19.2% (95 CIs 17.1%–21.3%)).

Conclusions

Counter intuitively, the prevalence of CMD is higher in occupational studies, compared to population studies (which include individuals not in employment), although this difference narrowed after accounting for measures of study quality, including response rate and sampling method. This finding is inconsistent with the healthy worker effect, which would presume lower levels of psychological symptoms in individuals in employment. One explanation is that the GHQ is sensitive to contextual factors, and it seems possible that symptoms of CMD are over reported when participants know that they have been recruited to a study on the basis that they belong to a specific occupational group, as in nearly all “stress” surveys.

Introduction

The general health questionnaire (GHQ) is one of the most commonly used measures to assess symptoms of common mental disorder (CMD) in the UK [1]. It has been administered in population studies (e.g. British Household Panel Survey) and more commonly in smaller studies of particular groups, such as occupational studies (e.g. a study of UK doctors [2]) to estimate the level of CMD in a specific population. It is generally believed that there are particular occupational groups who are exposed to a higher level of stress than other occupations, e.g. police officers and military personnel; however, there are few studies comparing rates of CMD across these occupations or to the general population.

UK prevalence estimates for common mental disorder from population studies are in the range of 14–17% [3], [4], with the prevalence of CMD in occupational studies, such as military personnel and London civil servants higher at 20% and 27% respectively [5], [6]. This difference is inconsistent with the ‘healthy worker effect’ and the assumption that healthier individuals are more likely to be selected into work, which is well established [7]. Furthermore, it is conflicting with the fact that there are many aspects of working which have a positive impact on mental health [8]. Occupational samples are also less likely to include the disabled, those with long term physical or mental health disorders, and by definition exclude the unemployed which in itself is a strong risk factor for poor mental health [9].

We have therefore undertaken a systematic review to identify UK studies that use the GHQ in either a population or an occupational setting and to examine whether a comparison between these types of surveys reveals a difference in the level of CMD caseness reported. The specific aim is to examine the prevalence of CMD caseness in all UK occupational and population studies, conducted from 1990 onwards, which have administered the GHQ, and to compare the weighted prevalence estimates between them.

Methods

Search strategy

The literature search was conducted in November 2011 using Medline, EMBASE and PsycInfo electronic databases to identify UK studies which had used the GHQ, covering the period from January 1990 to the date of the search. The search was restricted to UK studies due to the high quantity of international studies which have used the GHQ and also due to between country differences in occupational issues. The search terms were used as free text terms and were combined with Boolean operators. The initial search using the terms (general health questionnaire OR GHQ) was combined with (United Kingdom OR UK OR Britain OR England OR Wales OR Scotland OR Ireland OR Northern Ireland OR British Isles) using the AND operator.

Inclusion criteria

Inclusion criteria for occupational and population studies.

  1. The study should have administered the General Health Questionnaire
  2. The prevalence of CMD in the sample should be reported or available from the authors
  3. Conducted in the UK
  4. Sample size should be at least 100 participants
  5. Sample should not include children, adolescents (<18years) or student groups
  6. Should not use data from participants recruited in primary/secondary care, from GP records or who were recruited from a health care register

Inclusion criteria specific to occupational studies.

  1. The sample should be a particular occupational group(s)
  2. Studies on individuals in a trainee position in a particular occupation (e.g. clinical psychology trainees) were included, but other types of student groups (e.g. medical undergraduates) were excluded

Inclusion criteria specific to population studies.

  1. Should include at least 1000 participants (higher than for occupational studies because the sampling frame for population studies would be expected to be larger)
  2. Should not be a study of older adults (>60 y)

Data extraction and analysis

Data were independently extracted by two researchers (LG & IBZ). Data from 20 occupational and 10 population studies were extracted by both researchers and agreement between the researchers was high. The data extracted from the articles were: author, title and date of publication; information about the population and the location of the study; study design and type of sampling; number of participants and response rate; sample characteristics (e.g. gender split and age); which version of the GHQ questionnaire was administered and the cut-off used; and data on the prevalence of CMD. The numerator (the number of CMD cases) and the denominator (the sample size or number of participants who had data on CMD) were entered into the review database so that the prevalence (%) of CMD, standard errors and 95% confidence intervals (CI) could be calculated. Stata v11.0 was used for all data analyses [10] and meta analyses were conducted to produce weighted estimates and to examine the between study heterogeneity.

  1. The metan command was used to produce the forest plots, displaying the prevalence of CMD and 95% CIs for each sample, grouped by occupation for the occupational studies. Forest plots were produced across all of the occupational studies, displaying the weighted estimates by occupational group and overall across all of the studies. A further forest plot displayed the weighted estimates across the occupational studies and for the population studies, so that the estimates could be compared between these categories.
  2. To further investigate the issue of heterogeneity, and the difference between the two types of study, analyses were conducted which restricted the studies included to those which used the GHQ-12 version of the questionnaire and with a cut-off of 3/4 (41 occupational and 19 population studies) so that the prevalence estimates between studies should be more comparable. Random effects meta-analysis models were conducted within these restricted studies.
  3. Meta regressions were conducted using the metareg command to examine whether response rate (categorised as less than 50% vs. equal to or more than 50%) and sampling method (split into studies which used random sampling or aimed to recruit all participants from the sampling frame vs. studies which used non-random sampling) were associated with the prevalence of CMD. These variables were entered individually into meta regressions for the occupational and population studies separately.
  4. A further meta-analysis was conducted which restricted the studies to those with used the same version and cut-off of the GHQ, which was also restricted to studies which had a response rate of at least 50% and which used random sampling and a forest plot was produced displaying the weighted estimates for the occupational and the population studies.

Ethical approval

Ethical approval was not required for this systematic review.

Results

Study selection

The initial search terms general health questionnaire OR GHQ (restricted to abstracts in the English language and to the period from January 1990 – current) identified 10106 abstracts. A further search using the terms: United Kingdom OR UK OR Britain OR England OR Wales OR Scotland OR Ireland OR Northern Ireland OR British Isles was combined with the initial search using the AND operator, to restrict the search only to UK based studies. This reduced the number of abstracts to 1458 that met the initial search criteria: 494 of these abstracts were in Medline, 510 in EMBASE and 454 in PsycINFO. Examination of the titles revealed that 502 abstracts from the three databases were duplicates, so there were 956 articles that met the search criteria for this review.

Initial screening of the 956 abstracts showed that 262 of these were not relevant to the review, or were literature reviews. Further screening of the 694 remaining abstracts excluded a further 393 abstracts on the basis of the overall inclusion criteria with 301 abstracts remaining (see figure 1).

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Figure 1. PRISMA flow diagram showing the search process and selection of relevant abstracts.

https://doi.org/10.1371/journal.pone.0078693.g001

Selection of occupational studies

172 of these 301 abstracts were found to be occupational studies (see figure 1). Of these, 22 articles used data from the Whitehall II data and only the paper including data from the first wave was included, so a further 21 articles were excluded. 38 abstracts used data from the King's Centre for Military Health (KCMHR) military studies, of which 3 of the main studies were included in the review as the majority of the remaining papers used data from these same studies (or from a different phase of the same study). Therefore 56 papers were removed, which used these datasets, before the full articles were collated.

The 116 remaining articles were sent to full review, however, 27 did not provide data on the prevalence of CMD and this information was not available from the authors. Further reasons that papers were not included in the review included: 12 papers used the same data as another paper included in the review, 9 included samples <100 participants (this information was not apparent from the abstract), 3 papers did not collect data on CMD. 65 occupational papers were included in the final review for which data on CMD were available.

Selection of population studies

129 of the 301 abstracts were found to be population or household studies and the full articles were collated which were sent to review (see figure 1). Out of these, 16 studies did not include at least 1000 participants, 7 studies were of older adults and 7 were excluded which either did not administer the GHQ or the prevalence of CMD was not available.

Within the 99 remaining studies, there were 13 population based studies which were eligible for inclusion in the review and some of the population studies were reported in multiple abstracts (e.g. 38 used data from the British Household Panel Survey). There was also 5 out of the 99 studies that reported data from more than one population study.

There were 11 papers identified within the original search that included the relevant data on the prevalence of CMD for either one, or in some cases two, of the population studies (due to some papers reporting data from multiple population studies). The decision was made to report data from only one time-point/assessment for all of the longitudinal or repeated cross-sectional studies. Data was not available in the 11 identified papers for the Health Survey for England (data was extracted from an official published report from the NHS Information Centre), for the National Child Development Study (this data was extracted from the dataset by the researcher), for the Scottish Health Survey (extracted from an official report), nor for the West of Scotland Twenty-07 study (data extracted for the 3 age cohorts by the Twenty-07 data manager).

Data was therefore reported on 13 population studies: Aberdeen Children of the 1950s study; British Household Panel Survey wave 1; English and Welsh Civil and Social Justice Survey; Health and Lifestyle Survey; Health Survey for England 1995; MRC National Health and Development Study (GHQ administered at 53 y); National Child Development Study (GHQ administered at 42 y); Northern Ireland Health and Wellbeing Survey; Northern Ireland Household Panel Survey; Renfrew and Paisley (MIDSPAN) study; Scottish Health Survey 1995 wave; West of London Survey; West of Scotland Twenty-07 Study [which included 3 age cohorts: 1930s cohort, 1950s cohort, and 1970s cohort].

Occupational studies

Study characteristics.

Out of the 65 studies identified within this review (table 1), the majority had been conducted in health professionals and NHS staff (n = 41). Five had been carried out in military personnel, four in white collar workers, five in academics and teachers and the remaining 10 studies in social services staff, police, manual workers and chaplains. 47 studies recruited sample sizes ranging from 100 to 1000 participants; however, there were 18 studies which recruited a large sample, including a number of studies of NHS staff (e.g. a study of 1308 UK hospital consultants [11]), the Whitehall II study of civil servants (>10 000 staff from 20 London based civil service departments [6]) and studies of military personnel (e.g. a cross sectional survey of >10 000 UK armed forces personnel [5]). Twenty one studies used random sampling (or invited all participants in the sampling frame to participate in the study) and 44 used non-random sampling. Forty four studies had a response rate of at least 50%, 17 studies reported a response rate of less than 50% and 4 did not report this information.

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Table 1. Data extraction table for occupation studies (ordered by occupational group).

https://doi.org/10.1371/journal.pone.0078693.t001

How was common mental disorder measured?

The version of the GHQ that was administered varied between studies, in addition to the cut-off that was utilised. 49 assessed CMD using the GHQ-12, 14 used the GHQ-28, and 2 used the GHQ-30. 39 out of the 49 studies that administered the GHQ-12 used a cut-off of 3/4 as the criteria for being a case of CMD and 11 out of the 14 studies which used the GHQ-28 used a cut-off of 4/5, suggesting that these were the most common criteria for occupational studies which assess CMD.

Prevalence of common mental disorder.

Figure 2 displays the weighted estimates for CMD caseness across the different occupational groups, with an overall estimate of 31.6% (95% confidence intervals (CIs) 29.9–33.4%). There was evidence for high heterogeneity [12] from random effect models between the studies in all of the occupational groups (academics and teachers - I2 = 96.4%; health professionals and NHS staff - I2 = 96.3%; manual workers - I2 = 97.0%; military personnel - I2 = 99.0%; police - I2 = 97.7%; social services staff - I2 = 82.6%; white collar workers - I2 = 91.4%). The prevalence of CMD appears to be highest within the studies of academics/teachers (4 out of the 5 studies included academics working at a university) and social services staff, but the differences between the occupational groups were not statistically significant as the CIs overlapped. The weighted estimate for the prevalence of CMD in studies of academics and teachers was 37.2% (95% CIs 27.8–46.7%), in health professionals and NHS staff was 32.4% (95% CIs 30.0–34.7%), in manual workers was 28.4% (95% CIs 17.0–39.7%), in military personnel was 26.8% (95% CIs 20.7–33.0%), a prevalence of 24.3% (95% CIs 16.5–32.2%) in one study of chaplains, 31.4% (95% CIs 14.6–48.1%) in the police, 41.5% (95% CIs 34.4–48.5%) in social services staff and 23.9% (95% CIs 20.0–27.8%) in white collar workers. The lowest prevalence of CMD for an individual study was 14.5% in a study of white collar workers from 5 different organisations [13], with the highest in a study of substance misuse professionals of 82.4% [14].

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Figure 2. Forest plot displaying the weighted estimates for CMD caseness across the occupational groups.

https://doi.org/10.1371/journal.pone.0078693.g002

Occupational studies which used the GHQ-12 (cut-off 3/4).

There were 39 studies [2], [5], [11], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48] which used the same version of the questionnaire and cut-off, yet heterogeneity between these studies was still high overall (I2 = 97.4%) and within the different occupational groups (academics and teachers - I2 = 64.2%; health professionals and NHS staff - I2 = 96.9%; manual workers - I2 = 0.9%; military personnel - I2 = 98.6%; white collar workers - I2 = 91.8%), even when exactly the same questionnaire was administered. The weighted prevalence estimate for CMD across all of these occupational studies was 29.6% (95% CIs 27.3–31.9%), with 40.9% (95% CIs 36.6–45.2%) for academics and teachers, 30.3% (95% CIs 27.6–33.0%) for health professionals, 17.6% (95% CIs 16.0–19.3%) for manual workers, 25.7% (95% CIs 19.0–32.5%) for military personnel, 24.3% (95% CIs 16.5%–32.2%) in a study of chaplains, 36.0% (95% CIs 33.1–38.9%) in one study of social services staff and 20.3% (95% CIs 8.7–31.8%) for white collar workers. Figure 3 displays the weighted estimates in these restricted studies.

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Figure 3. Forest plot displaying the weighted estimates for CMD caseness across the occupational groups (restricted to studies using GHQ-12 (3/4)).

https://doi.org/10.1371/journal.pone.0078693.g003

Occupational studies which used the GHQ-12 (cut-off 3/4), random sampling and had a response rate ≥50%.

In univariate meta regression analyses, neither the variable identifying studies as having conducted random sampling (β = 0.00, se[β] = 0.03, p = 0.93), nor that representing having a response rate ≥50% (β = −0.11, se[β] = 0.10, p = 0.28) were associated with the prevalence of CMD in the restricted occupational studies.

The meta-analysis restricted to the 10 studies [2], [5], [27], [33], [36], [37], [38], [39], [47], [48] which used the same version of the GHQ and the same cut-off, in addition to those which conducted random sampling, with a response rate of at least 50%, resulted in a lower overall prevalence estimate for CMD of 23.9% (95% CIs 20.5–27.4%), with less difference between the occupational groups which were represented in the studies that met these criteria: 21.5% (95% CIs 15.3–27.7%) for health professionals, 25.7% (95% CIs 19.0–32.5%) for military personnel, 24.3% (95% CIs 16.5%–32.2%) in a study of chaplains and 26.3% (95% CIs 21.1–31.5%) in a study of white collar workers.

Population studies

Study characteristics.

There were 13 population studies which had administered the GHQ, with the West of Scotland Twenty-07 study including 3 separate age cohorts, so there were 15 studies in total. The British Household Panel Survey, Health and Lifestyle Survey, MRC National Health and Development Study and the National Child Development Study all reported data from England, Scotland and Wales, with the English and Welsh Civil and Social Justice Survey only reporting data from two countries. The remaining studies included participants either from a single country (e.g. the Health Survey for England) or from a particular region in the UK (e.g. the Aberdeen Children of the 1950s Study) (table 2). All of the studies used random sampling or invited all participants in the sampling frame to participate in the study. Fourteen of the studies reported the response rate and 13 of these had a response rate of at least 50%.

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Table 2. Data extraction table for population studies (ordered by name of study).

https://doi.org/10.1371/journal.pone.0078693.t002

How was common mental disorder measured?

Eight of the 13 population studies administered the GHQ-12, with the most commonly used cut-off of 3/4. The follow-up to the Aberdeen Children of the 1950s study used a reduced 4-item version of the GHQ with a cut-off of 0/1. The MRC National Health and Development Study used the GHQ-28 (5/6) and the remaining three studies used the GHQ-30 (two with a 4/5 cut-off and the Renfrew & Paisley study with a particularly low 3/4 cut-off).

Prevalence of common mental disorder.

Figure 4 displays the weighted estimates for CMD caseness for the population and occupational studies, showing that the estimate was 20.4% (95% CIs 18.2–22.6%) for population studies and there was high heterogeneity (I2 = 98.4%). The prevalence across the studies ranged from 14.0% scoring above the cut-off for symptoms of CMD in the English and Welsh Civil and Social Justice Survey to 31.2% in the Health and Lifestyle Survey.

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Figure 4. Forest plot displaying the weighted estimates for CMD caseness between the occupational and population studies.

https://doi.org/10.1371/journal.pone.0078693.g004

Population studies which used the GHQ-12 (cut-off 3/4).

There were 9 studies [49], [50], [51], [52], [53], [54], [55] that used the same questionnaire and cut-off and there was high heterogeneity between these studies (I2 = 95.5%). The weighted prevalence estimate (see figure 5) across these studies was 19.1% (95% CIs 17.3–20.8%).

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Figure 5. Forest plot displaying the weighted estimates for CMD caseness between the occupational and population studies (restricted to studies using GHQ-12 (3/4)).

https://doi.org/10.1371/journal.pone.0078693.g005

Population studies which used the GHQ-12 (cut-off 3/4), random sampling and had a response rate ≥50%.

In a univariate meta regression analysis, having a response rate ≥50% (β = −0.06, se[β] = 0.16, p = 0.72) was not associated with the prevalence of CMD in the restricted population studies. The meta-analysis restricted to the 7 studies [49], [50], [51], [52], [54], [55]which used the same version of the GHQ and the same cut-off, in addition to those which conducted random sampling, with a response rate of at least 50%, reported a prevalence estimate of CMD of 19.2% (95% CIs 17.1–21.3%), with evidence for high heterogeneity between these restricted studies (I2 = 96.4%).

Comparing the prevalence of CMD in occupational and population studies

Figure 4 highlights the trend for the weighted estimates of CMD to be higher overall in occupational studies, regardless of the occupational group, compared to the population studies and the confidence intervals do not overlap suggesting that the difference is statistically significant. When restricted to studies that used GHQ-12 (cut-off 3/4) the prevalence estimates (see figure 5) also suggest that the prevalence is significantly higher in occupational studies compared to population studies, but the differences is reduced and no longer significant after further restricting by response rate and sampling method (see figure 6; occupational studies −23.9%, 95% CIs 20.5%–27.4%; population studies −19.2%, 95 CIs 17.1%–21.3%).

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Figure 6. Forest plot displaying the weighted estimates for CMD caseness between the occupational and population studies (restricted to studies using GHQ-12 (3/4), response rate ≥50% & random sampling).

https://doi.org/10.1371/journal.pone.0078693.g006

Discussion

The main finding of this systematic review is that people appear less likely to report symptoms of CMD in the context of a population based study rather than in a study of the occupational group to which they belong. This difference was reduced but not fully accounted for by differences between these types of studies, in relation to the quality of the studies. This effect is unlikely to reflect true differences in the level of CMD symptoms experienced, because population studies aim to comprise all sections of the population, including those with chronic health problems, long term disabilities and the unemployed, whilst occupational studies will be subject to the health worker effect [7]; so one would anticipate the reverse. There are aspects of work which are associated with increased psychological distress (e.g. high demands and low decision latitude [56]), however, the benefits of employment, over not working, for mental health have consistently been outlined and it is established that the prevalence of CMD is lower in working populations compared to the general population [57]. There were also unexpected findings within the occupational groups: occupations for which one would expect a higher level of traumatic events, such as the military and police, were not found to have a higher prevalence of CMD than other occupational groups, including academics, teachers, white collar workers and social services staff.

We propose that studies directed at the mental health or “stress levels” of particular occupations may be subjected to a systematic bias, one that is not present in true population studies when participants are not selected purely because they belong to a specific occupation. Numerous occupational studies are actually labelled as studies of “work stress”, which may give rise to a framing effect. There is evidence for strong contextual effects in previous experimental and observational studies [58], [59], [60], [61], which can be defined as the effect of environmental factors on subjective outcomes, in addition to bias in self-report psychological measures [62]. The setting in which a questionnaire is completed is likely to influence responses. Responses in the occupational studies may have been biased by a framing effect [63], with the emphasis on job related questions potentially leading to individuals venting their work frustrations through questionnaires which provide an opportunity to report dissatisfaction. This framing effect may be heightened, or conversely lessened, depending on where the GHQ is embedded within the questionnaire and its positioning relative to other psychosocial measures.

Within the occupational groups certain other trends also became apparent, before any restrictions had been made to the meta-analyses. This study was constrained to published research studies (so we did not have data on all occupational groups in the UK), but the overall findings suggested that teachers and academics (with this category predominantly comprising studies of university academics) and social services staff had higher levels of CMD (although the differences were not statistically significant). There is further evidence for higher rates of CMD in teachers in other studies. Analyses of the 2000 UK Adult Psychiatric Morbidity Survey showed that the prevalence of psychological disorder was highest in managers & administrators, teaching professionals, other associate professionals, clerical and secretarial, ‘other’ sales and personal service occupations. However the prevalence of psychological disorder was higher in primary and secondary teachers, compared to higher education teachers [64], so is not completely in agreement with this review which predominantly included university academics. A further study examining sickness absence from 2001 to 2007 in the Netherlands showed that the percentage of sick days due to CMD was highest in the education sector, followed by financial services and health care sectors [65]. The Adult Psychiatric Morbidity Survey is a population study and the latter study measured actual behaviour in response to CMD, suggesting that the difference between occupational groups is unlikely to be a consequence of contextual effects which seem to be stable across occupations.

A surprising finding within this review was the variation in prevalence estimates for CMD caseness between the population studies, even when restricted to those which used the same questionnaire and threshold. The population studies identified within this review are often used as a population reference for measures of mental health [66], but this study shows that the comparison may differ depending on which population study is chosen. Whilst both the British Household Panel Survey and Health Survey for England are considered to recruit representative samples, there is still a difference between the prevalence of CMD caseness for these surveys, indicating that this either results from a sampling effect or from the sensitivity of the GHQ to other factors which may differ between surveys. These include the position of the GHQ within the overall questionnaire, the length of a questionnaire and finally whether it was self-completion or interview administered.

Strengths and weaknesses

We have conducted a comprehensive review of all papers published since 1990 that have administered the GHQ, within the two areas of research in which this questionnaire is most commonly used, both occupational and population research. This is the first study of which we are aware to compare occupational and population rates of CMD, that is not restricted to a particular occupation. Weaknesses of this review include the fact that the majority of occupational studies of mental health have been conducted within health professionals, most likely due to the salience of these issues to the authors, and there were fewer studies in occupations that are considered to be at a high risk of stress, such as the police. The version of the GHQ administered differed between studies, in addition to the cut-off that was applied. Whilst we tried to control for this by restricting some of the analyses to comparable studies, this is a general limitation of comparisons between GHQ studies which is not always taken into account by study authors. However, the findings do not suggest that the studies with the highest prevalence were those using the lowest cut-off. Further limitations include the sampling differences between the population studies and the difference in location both within the population studies and between the population and the occupational studies. The majority of the occupational studies were conducted in a specific area as opposed to being national studies of a particular occupation. There was also evidence that in general the population based studies were of a higher quality than occupational studies, and the difference between them was reduced after making restrictions to the meta-analysis based on study quality. Finally, there was very high heterogeneity in the meta analyses of both the occupational and population data, which remained when the studies included in the meta-analysis were restricted to be more comparable [67], [68].

Implications

The primary implication of this research relates to the sensitivity of the GHQ, which asks about ‘recent’ symptoms of mental health, to factors other than objective mental health and to the potential framing effect resulting from the overall narrative of a questionnaire or interview. However, we suggest that other self-reported measures of mental health may be subject to contextual effects, and that interpreting the results of any single study without considering the context in which it was given, and the possible bias that introduces, may lead to flawed conclusions. Hence for example, if an individual reports higher levels of psychological symptoms within the context of an occupational study, this may be a reflection of dissatisfaction with their job as opposed to reflecting depression or unhappiness with their life outside of work. These types of effects have previously been shown in individual studies, but we have systematically reviewed evidence across a range of studies. The elevated levels of CMD evidenced in occupational studies may be reduced if mental health is assessed separately to job satisfaction and other occupational constructs and thought should be given as to where the mental health measures are incorporated in a questionnaire.

Conclusions

This review has shown that more individuals scored above the threshold for CMD caseness in occupational studies, compared to population studies, even when accounting for the version of the questionnaire that was administered and the threshold used to classify CMD. We propose that this difference may have resulted from the context of the occupational studies resulting in higher reports of psychological symptoms, in addition to differences between these types of studies in study quality.

Supporting Information

Acknowledgments

We would like to thank Rebecca Hardy and William Lee for their helpful comments on the meta analysis.

Author Contributions

Conceived and designed the experiments: SW LG MH NTF. Analyzed the data: LG IBZ. Wrote the paper: LG. Interpreted the findings of the analysis: LG SW MH NTF. Critical revisions of the article: LG SW MH NTF SAS.

References

  1. 1. Goldberg DP (1972) The detection of psychiatric illness by questionnaire. Maudsley Monograph No. 21 . Oxford: Oxford University Press.
  2. 2. McManus IC, Winder BC, Gordon D (1999) Are UK doctors particularly stressed? The Lancet 354: 1358–1359.
  3. 3. Craig R, Mindell J, Hirani V, (2009) Health Survey for England 2008. London: The Information Centre.
  4. 4. Bara AC, Arber S (2009) Working shifts and mental health–findings from the British Household Panel Survey (1995–2005). Scand J Work Environ Health 35: 361–367.
  5. 5. Hotopf M, Hull L, Fear NT, Browne T, Horn O, et al. (2006) The health of UK military personnel who deployed to the 2003 Iraq war: a cohort study. The Lancet 367: 1731–1741.
  6. 6. Stansfeld SA, Fuhrer R, Shipley MJ, Marmot MG (2002) Psychological distress as a risk factor for coronary heart disease in the Whitehall II Study. International Journal of Epidemiology 31: 248–255.
  7. 7. Li C-Y, Sung F-C (1999) A review of the healthy worker effect in occupational epidemiology. Occupational Medicine 49: 225–229.
  8. 8. Waddell G, Britain G, Burton AK (2006) Is work good for your health and well-being? London: TSO (The Stationery Office).
  9. 9. Booker CL, Sacker A (2011) Psychological well-being and reactions to multiple unemployment events: adaptation or sensitisation? Journal of Epidemiology and Community Health.
  10. 10. StataCorp (2009) Stata Statistical Software: Release 11. College Station, TX: Stata Corporation.
  11. 11. Taylor C, Graham J, Potts HWW, Richards MA, Ramirez AJ (2005) Changes in mental health of UK hospital consultants since the mid-1990s. The Lancet 366: 742–744.
  12. 12. Higgins JPT, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327: 557–560.
  13. 13. Bond FW, Donaldson-Feilder EJ (2004) The relative importance of psychological acceptance and emotional intelligence to workplace well-being. British Journal of Guidance & Counselling 32: 187–203.
  14. 14. Oyefeso A, Clancy C, Farmer R (2008) Prevalence and associated factors in burnout and psychological morbidity among substance misuse professionals. BMC Health Services Research 8: 39.
  15. 15. Berman R, Campbell M, Makin W, Todd C (2007) Occupational stress in palliative medicine, medical oncology and clinical oncology specialist registrars. Clinical Medicine, Journal of the Royal College of Physicians 7: 235–242.
  16. 16. Burbeck R, Coomber S, Robinson SM, Todd C (2002) Occupational stress in consultants in accident and emergency medicine: a national survey of levels of stress at work. Emergency Medicine Journal 19: 234–238.
  17. 17. Calnan M, Wainwright D, Forsythe M, Wall B, Almond S (2001) Mental health and stress in the workplace: the case of general practice in the UK. Social Science & Medicine 52: 499–507.
  18. 18. Catt S, Fallowfield L, Jenkins V, Langridge C, Cox A (2005) The informational roles and psychological health of members of 10 oncology multidisciplinary teams in the UK. Br J Cancer 93: 1092–1097.
  19. 19. Coomber S, Todd C, Park G, Baxter P, Firth-Cozens J, et al. (2002) Stress in UK intensive care unit doctors. British Journal of Anaesthesia 89: 873–881.
  20. 20. Evans S, Huxley P, Gately C, Webber M, Mears A, et al. (2006) Mental health, burnout and job satisfaction among mental health social workers in England and Wales. The British Journal of Psychiatry 188: 75–80.
  21. 21. Gorter RC, Freeman R (2011) Burnout and engagement in relation with job demands and resources among dental staff in Northern Ireland. Community Dentistry and Oral Epidemiology 39: 87–95.
  22. 22. Guthrie E, Tattan T, Williams E, Black D, Bacliocotti H (1999) Sources of stress, psychological distress and burnout in psychiatrists. Psychiatric Bulletin 23: 207–212.
  23. 23. Hardy GE, Shapiro DA, Haynes CE, Rick JE (1999) Validation of the General Health Questionnaire-12: Using a sample of employees from England's health care services. Psychological Assessment 11: 159–165.
  24. 24. Hughes EL, Parkes KR (2007) Work hours and well-being: The roles of work-time control and work–family interference. Work & Stress 21: 264–278.
  25. 25. Kumary A, Baker M (2008) Stresses reported by UK trainee counselling psychologists. Counselling Psychology Quarterly 21: 19–28.
  26. 26. Loretto W, Platt S, Popham F (2010) Workplace Change and Employee Mental Health: Results from a Longitudinal Study. British Journal of Management 21: 526–540.
  27. 27. McManus IC, Gordon D, Winder BC (2000) Duties of a doctor: UK doctors and Good Medical Practice. Quality in Health Care 9: 14–22.
  28. 28. McManus IC, Winder B, Paice E (2002) How consultants, hospitals, trusts and deaneries affect pre-registration house officer posts: a multilevel model. Medical Education 36: 35–44.
  29. 29. McManus IC, Smithers E, Partridge P, Keeling A, Fleming PR (2003) A levels and intelligence as predictors of medical careers in UK doctors: 20 year prospective study. BMJ 327: 139–142.
  30. 30. McManus I, Keeling A, Paice E (2004) Stress, burnout and doctors' attitudes to work are determined by personality and learning style: A twelve year longitudinal study of UK medical graduates. BMC Medicine 2: 29.
  31. 31. Paice E, Rutter H, Wetherell M, Winder B, McManus IC (2002) Stressful incidents, stress and coping strategies in the pre-registration house officer year. Medical Education 36: 56–65.
  32. 32. Ramirez AJ, Graham J, Richards MA, Cull A, Gregory WM, et al. (1995) Burnout and psychiatric disorder among cancer clinicians. Br J Cancer 71: 1263–1269.
  33. 33. Ramirez AJ, Graham J, Richards MA, Gregory WM, Cull A (1996) Mental health of hospital consultants: the effects of stress and satisfaction at work. The Lancet 347: 724–728.
  34. 34. Sharma A, Sharp DM, Walker LG, Monson JRT (2008a) Stress and burnout among colorectal surgeons and colorectal nurse specialists working in the National Health Service. Colorectal Disease 10: 397–406.
  35. 35. Sharma A, Sharp DM, Walker LG, Monson JRT (2008b) Stress and burnout in colorectal and vascular surgical consultants working in the UK National Health Service. Psycho-Oncology 17: 570–576.
  36. 36. Wall TD, Bolden RI, Borrill CS, Carter AJ, Golya DA, et al. (1997) Minor psychiatric disorder in NHS trust staff: occupational and gender differences. The British Journal of Psychiatry 171: 519–523.
  37. 37. Bridger R, Kilminster S, Slaven G (2007) Occupational stress and strain in the naval service: 1999 and 2004. Occupational Medicine 57: 92–97.
  38. 38. Bridger RS, Brasher K, Dew A, Kilminster S (2008) Occupational stress and strain in the Royal Navy 2007. Occupational Medicine 58: 534–539.
  39. 39. Jones M, Rona RJ, Hooper R, Wessely S (2006) The burden of psychological symptoms in UK Armed Forces. Occupational Medicine 56: 322–328.
  40. 40. Coffey M, Dugdill L, Tattersall A (2004) Stress in Social Services: Mental Wellbeing, Constraints and Job Satisfaction. British Journal of Social Work 34: 735–746.
  41. 41. Hussain T (2004) Musculoskeletal symptoms among truck assembly workers. Occupational Medicine 54: 506–512.
  42. 42. Wadsworth EJK, Allen PH, McNamara RL, Smith AP (2008) Fatigue and health in a seafaring population. Occupational Medicine 58: 198–204.
  43. 43. Kinman G, Jones F (2008a) Effort-reward imbalance and overcommitment: Predicting strain in academic employees in the United Kingdom. International Journal of Stress Management 15: 381–395.
  44. 44. Kinman G (2008b) Work stressors, health and sense of coherence in UK academic employees. Educational Psychology 28: 823–835.
  45. 45. McClenahan CA, Giles ML, Mallett J (2007) The importance of context specificity in work stress research: A test of the Demand-Control-Support model in academics. Work & Stress 21: 85–95.
  46. 46. Miller GVF, Travers CJ (2005) Ethnicity and the experience of work: Job stress and satisfaction of minority ethnic teachers in the UK. International Review of Psychiatry 17: 317–327.
  47. 47. Guppy A, Weatherstone L (1997) Coping strategies, dysfunctional attitudes and psychological well-being in white collar public sector employees. Work & Stress 11: 58–67.
  48. 48. Lloyd-Williams M, Wright M, Cobb M, Shiels C (2004) A prospective study of the roles, responsibilities and stresses of chaplains working within a hospice. Palliat Med 18: 638–645.
  49. 49. Balmer NJ, Pleasence P, Buck A (2010) Psychiatric morbidity and people's experience of and response to social problems involving rights. Health & Social Care in the Community 18: 588–597.
  50. 50. Prescott-Clarke P, Primatesta P, (1997) Health Survey for England 1995. London: The Stationery Office.
  51. 51. Power C, Elliott J (2006) Cohort profile: 1958 British birth cohort (National Child Development Study). International Journal of Epidemiology 35: 34–41.
  52. 52. O'Reilly D, Stevenson M (2003) Mental health in Northern Ireland: have “the Troubles” made it worse? Journal of Epidemiology and Community Health 57: 488–492.
  53. 53. Murphy H, Lloyd K (2007) Civil Conflict in Northern Ireland and the Prevalence of Psychiatric Disturbance Across the United Kingdom: a Population Study Using the British Household Panel Survey and the Northern Ireland Household Panel Survey. International Journal of Social Psychiatry 53: 397–407.
  54. 54. Dong W, Erens B, (1997) Scotland's Health: Scottish Health Survey 1995. Edinburgh: The Stationery Office.
  55. 55. Benzeval M, Der G, Ellaway A, Hunt K, Sweeting H, et al. (2009) Cohort Profile: West of Scotland Twenty-07 Study: Health in the Community. International Journal of Epidemiology 38: 1215–1223.
  56. 56. Stansfeld S (2002) Work, personality and mental health. The British Journal of Psychiatry 181: 96–98.
  57. 57. Ford E, Clark C, McManus S, Harris J, Jenkins R, et al. (2010) Common mental disorders, unemployment and welfare benefits in England. Public Health 124: 675–681.
  58. 58. Pennebaker JW, Lightner J (1980) Competition of internal and external information in an exercise setting. Journal of Personality and Social Psychology 39: 165–174.
  59. 59. Eich E, Macaulay D (2000) Are Real Moods Required to Reveal Mood-Congruent and Mood-Dependent Memory? Psychological Science 11: 244–248.
  60. 60. Bogaerts K, Notebaert K, Van Diest I, Devriese S, De Peuter S, et al. (2005) Accuracy of respiratory symptom perception in different affective contexts. J Psychosom Res 58: 537–543.
  61. 61. LaGuardia RL, Smith G, Francois R, Bachman L (1983) Incidence of delayed stress disorder among Vietnam era veterans. American Journal of Orthopsychiatry 53: 18–26.
  62. 62. Macleod J, Smith GD, Heslop P, Metcalfe C, Carroll D, et al. (2002) Psychological stress and cardiovascular disease: empirical demonstration of bias in a prospective observational study of Scottish men. BMJ 324: 1247.
  63. 63. Tversky A, Kahneman D (1981) The framing of decisions and the psychology of choice. Science 211: 453–458.
  64. 64. Stansfeld S, Head J, Rasul F, Singleton N, Lee A (2003) Occupation and mental health: Secondary analyses of the ONS Psychiatric Morbidity Survey of Great Britain. London: Health & Safety Executive.
  65. 65. Roelen CAM, Koopmans PC, Hoedeman R, Bültmann U, Groothoff JW, et al. (2009) Trends in the incidence of sickness absence due to common mental disorders between 2001 and 2007 in the Netherlands. The European Journal of Public Health 19: 625–630.
  66. 66. Bowling A, Bond M, Jenkinson C, Lamping D (1999) Short Form 36 (SF-36) Health Survey questionnaire: which normative data should be used? Comparisons between the norms provided by the Omnibus Survey in Britain, the Health Survey for England and the Oxford Healthy Life Survey. Journal of Public Health 21: 255–270.
  67. 67. Higgins JPT (2008) Commentary: Heterogeneity in meta-analysis should be expected and appropriately quantified. International Journal of Epidemiology 37: 1158–1160.
  68. 68. Riley RD, Higgins JPT, Deeks JJ (2011) Interpretation of random effects meta-analyses. BMJ 342..
  69. 69. Emslie C, Fuhrer R, Hunt K, Macintyre S, Shipley M, et al. (2002) Gender differences in mental health: evidence from three organisations. Social Science & Medicine 54: 621–624.
  70. 70. Alexander DA, Klein S (2001) Ambulance personnel and critical incidents. The British Journal of Psychiatry 178: 76–81.
  71. 71. Appleton K, House A, Dowell A (1998) A survey of job satisfaction, sources of stress and psychological symptoms among general practitioners in Leeds. Br J Gen Pract 48: 1059–1063.
  72. 72. Baldwin PJ, Dodd M, Wrate RM (1997) Young doctors' health–II. Health and health behaviour. Social Science & Medicine 45: 41–44.
  73. 73. Bamber M, McMahon R (2008) Danger–early maladaptive schemas at work!: the role of early maladaptive schemas in career choice and the development of occupational stress in health workers. Clinical Psychology & Psychotherapy 15: 96–112.
  74. 74. Butterworth T, Carson J, Jeacock J, White E, Clements A (1999) Stress, coping, burnout and job satisfaction in British nurses: findings from the Clinical Supervision Evaluation Project. Stress Medicine 15: 27–33.
  75. 75. Caplan RP (1994) Stress, anxiety, and depression in hospital consultants, general practitioners, and senior health service managers. BMJ 309: 1261–1263.
  76. 76. Cushway D (1992) Stress in clinical psychology trainees. British Journal of Clinical Psychology 31: 169–179.
  77. 77. Cushway D, Tyler PA (1994) Stress and coping in clinical psychologists. Stress Medicine 10: 35–42.
  78. 78. Edwards D, Burnard P, Coyle D, Fothergill A, Hannigan B (2000) Stressors, moderators and stress outcomes: findings from the All-Wales Community Mental Health Nurse Study. Journal of Psychiatric and Mental Health Nursing 7: 529–537.
  79. 79. Fagin L, Brown D, Rmn HB, Leary J, Carson J (1995) The Claybury community psychiatric nurse stress study: is it more stressful to work in hospital or the community? Journal of Advanced Nursing 22: 347–358.
  80. 80. Glozier N, Hough C, Henderson M, Holland-Elliott K (2006) Attitudes of Nursing Staff Towards Co-Workers Returning from Psychiatric and Physical Illnesses. International Journal of Social Psychiatry 52: 525–534.
  81. 81. Macpherson R, Eastley RJ, Richards H, Mian IH (1994) Psychological distress among workers caring for the elderly. International Journal of Geriatric Psychiatry 9: 381–386.
  82. 82. McKinstry B, Porter M, Wrate R, Elton R, Shaw J (2004) The MAGPI (Morale Assessment in General Practice Index): a new way for doctors to self-assess their morale. Education for Primary Care 15: 231–241.
  83. 83. Patterson ID, Bell JS (2000) Supporting staff in employment: the emotional wellbeing of staff in an NHS psychiatric hospital. Health Bull (Edinb) 58: 403–407.
  84. 84. Sheikh A, Hurwitz B (2000) Psychological morbidity in general practice managers: a descriptive and explanatory study. British Journal of General Practice 50: 203–206.
  85. 85. Tyler PA, Carroll D, Cunningham SE (1991) Stress and well-being in nurses: a comparison of the public and private sectors. International Journal of Nursing Studies 28: 125–130.
  86. 86. Wray J, Aspland J, Gibson H, Stimpson A, Watson R (2009) “A wealth of knowledge”: A survey of the employment experiences of older nurses and midwives in the NHS. International Journal of Nursing Studies 46: 977–985.
  87. 87. Avery AJ, Betts DS, Whittington A, Heron TB, Wilson SH, et al. (1998) The mental and physical health of miners following the 1992 national pit closure programme: a cross sectional survey using General Health Questionnaire GHQ-12 and Short Form SF-36. Public Health 112: 169–173.
  88. 88. Booth NJ, Lloyd K (2000) Stress in Farmers. International Journal of Social Psychiatry 46: 67–73.
  89. 89. Unwin C, Blatchley N, Coker W, Ferry S, Hotopf M, et al. (1999) Health of UK servicemen who served in Persian Gulf War. The Lancet 353: 169–178.
  90. 90. Biggam FH, Power KG, Macdonald RR (1997) Coping with the occupational stressors of police work: a study of Scottish Officers. Stress Medicine 13: 109–115.
  91. 91. Brown J, Fielding J, Grover J (1999) Distinguishing traumatic, vicarious and routine operational stressor exposure and attendant adverse consequences in a sample of police officers. Work and Stress 13: 312–325.
  92. 92. Kinman G, Grant L (2011) Exploring Stress Resilience in Trainee Social Workers: The Role of Emotional and Social Competencies. British Journal of Social Work 41: 261–275.
  93. 93. Emslie C, Hunt K, Macintyre S (1999) Problematizing gender, work and health: the relationship between gender, occupational grade, working conditions and minor morbidity in full-time bank employees. Social Science & Medicine 48: 33–48.
  94. 94. Stansfeld SA, Marmot MG (1992) Social class and minor psychiatric disorder in British Civil Servants: a validated screening survey using the General Health Questionnaire. Psychol Med 22: 739–749.
  95. 95. Dundas R, Leyland AH, Macintyre S, Leon DA (2006) Does the primary school attended influence self-reported health or its risk factors in later life? Aberdeen Children of the 1950s Study. International Journal of Epidemiology 35: 458–465.
  96. 96. Weich S, Lewis G, Jenkins SP (2001) Income inequality and the prevalence of common mental disorders in Britain. The British Journal of Psychiatry 178: 222–227.
  97. 97. Lewis G, Wilkinson G (1993) Another British disease? A recent increase in the prevalence of psychiatric morbidity. J Epidemiol Community Health 47: 358–361.
  98. 98. Hatch SL, Mishra G, Hotopf M, Jones PB, Kuh D (2009) Appraisals of stressors and common mental disorder from early to mid-adulthood in the 1946 British birth cohort. Journal of Affective Disorders 119: 66–75.
  99. 99. Pembroke TPI, Rasul F, Hart CL, Davey Smith G, Stansfeld SA (2006) Psychological distress and chronic obstructive pulmonary disease in the Renfrew and Paisley (MIDSPAN) study. Journal of Epidemiology and Community Health 60: 789–792.