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Activated α2-Macroglobulin Binding to Cell Surface GRP78 Induces T-Loop Phosphorylation of Akt1 by PDK1 in Association with Raptor

Figure 6

A schematic diagram showing the possible mechanism of Raptor-mediated phosphorylation of Akt at Thr308 by PDK1.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0088373.g006