Skip to main content
Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Immune Status, Strain Background, and Anatomic Site of Inoculation Affect Mouse Papillomavirus (MmuPV1) Induction of Exophytic Papillomas or Endophytic Trichoblastomas

Figure 7

Dysregulated gene networks.

Twenty-nine probe sets (representing 26 genes) were identified as uniquely dysregulated in the differential expression analyses of dorsal versus tail lesions and dorsal versus facial lesions. These 26 genes were used as input in Ingenuity's Pathway Analysis tool. This tool generates networks by attempting to connect submitted genes of interest together using Ingenuity’s Knowledge Base constructed from curated literature. The cell morphology and connective tissue-associated cancer network (A) and the cellular development and growth-associated cancer network (B) are (statistically) significantly associated with the function of cancer. Red is upregulation while green is downregulation.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0113582.g007