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Agrin and Perlecan Mediate Tumorigenic Processes in Oral Squamous Cell Carcinoma

Figure 6

Viability of SCC-9 LN-1 and A431 cell lines in 10 µM of cisplatin treatment.

At 10 µM of cisplatin, the viability of SCC-9 (n = 3, A), SCC-9 LN-1 (n = 3, B) and A431 (n = 3C) was significantly reduced when agrin was silenced. Only in A431 cell line the same result of decreasing in viability was observed for perlecan siRNA-knockdown (C) (One-way ANOVA followed by Tukey’s test, different letters indicate statistically difference at p<0.05).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0115004.g006