The PKC-β selective inhibitor, Enzastaurin, impairs memory in middle-aged rats
Fig 3
ENZ treated and control groups demonstrate similar performance in the Morris Water Maze probe trial.
During the probe trial, both ENZ-treated and vehicle-treated groups swam for a significantly higher percentage of distance in the quadrant that included the platform during previous testing days in comparison to the opposite quadrant. This indicates that ENZ treatment did not decrease the ability to locate the quadrant in which the platform should be.