Reduction in terminally differentiated T cells in virologically controlled HIV-infected aging patients on long-term antiretroviral therapy
Fig 3
Reduced frequencies of CD28-, CD27- and CD57+ T cells in HIV-infected patients with controlled viremia on ART with increasing CD4 T cell counts.
Frequencies of CD28+/CD28- cells (A), CD27+/CD27- cells (B), CD57+/CD57- cells (C) within the CD4+ T cell population plotted with increasing CD4 T cell counts in HIV+ and UNC. Frequencies of CD28+/CD28- cells (D), CD27+/CD27- cells (E), CD57+/CD57- cells (F) within the CD8+ T cell population plotted with increasing CD4 T cell counts in HIV+ and UNC. (n = 100 HIV+, n = 75 UNC) (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001).