Reduction in terminally differentiated T cells in virologically controlled HIV-infected aging patients on long-term antiretroviral therapy
Fig 6
Recovery of CD4+ and CD8+ naïve to memory T cell ratios in HIV-infected patients with controlled viremia on ART.
Frequencies of naïve (N, CD28IntCD95LoCD45RAHiCCR7Hi) CD4+ T cells (A), and CD8+ T cells (B) plotted with increasing CD4 T cell counts in HIV+ and UNC. Frequencies of CD31+ and CD31- cells on naïve CD4+ T cells (C), and naïve CD8+ T cells (D) in HIV+ and UNC. Frequencies of CD31+ and CD31- cells on naïve CD4+ T cells (E), and naïve CD8+ T cells (F) plotted with increasing CD4 T cell counts in HIV+ and UNC. (n = 100 HIV+, n = 75 UNC) (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001).