Reduction in terminally differentiated T cells in virologically controlled HIV-infected aging patients on long-term antiretroviral therapy
Fig 7
Evaluation of CD4+ T cell function, IL-2, IL-10 and IFN-γ production, in HIV-infected patients with controlled viremia on ART.
Frequencies of unstimulated and PMA stimulated IL-2 (A), IL-10 (C) and IFN-γ (E) CD4+ T cells in HIV+ and UNC. Frequencies of unstimulated and PMA stimulated IL-2 (B) IL-10 (D), IFN-γ (F) CD4+ T cells plotted with increasing CD4 T cell counts in HIV+ and UNC. (n = 100 HIV+, n = 75 UNC) (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001).