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A Metazoan/Plant-like Capping Enzyme and Cap Modified Nucleotides in the Unicellular Eukaryote Trichomonas vaginalis

Figure 8

Phylogenetic analysis of TvCE.

Protein maximum likelihood phylogeny recovered for 37 GTases functioning with TPaseMDP and TPasePL-GTases configured enzymes that maximizes taxonomic diversity. A clan of all TPasePL-GTases, that includes TvCE, is boxed and shaded. Numbers indicate the bootstrap proportion (BP) support values (>50% are shown). Boxed values list BP for alternative analyses where the indicated sequences were removed; V&G indicates removal of both the viral and Giardia sequences. The tree was rooted on Giardia lamblia, the most divergent sequence (broken branch to fit and true branch length value indicated). Removal of either one or the two most divergent sequences (Giardia and the iridovirus) did not affect the overall tree topology (see Data S1; Figure S4). Higher taxonomic terms [24], [28] are indicated. Species names abbreviated with the first three letters of the genus and species are all listed in full in Table S1 - with corresponding accession numbers. The scale bar indicates inferred number of substitutions per site.

Figure 8

doi: https://doi.org/10.1371/journal.ppat.1000999.g008