Figures
Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System
Mixed primary cultures from BALB/c mice brain infected with HCoV-OC43 (rOC/SG758R). Viral spreading was evaluated at 24 hours post-infection. Neurons were stained for microtubule-associated protein 2 (MAP2) (green) and the HCoV-OC43 S viral glycoprotein (red). Nuclei were stained in blue with DAPI. Magnification 200x. Talbot et al.
Image Credit: Talbot et al.
Citation: (2015) PLoS Pathogens Issue Image | Vol. 11(11) November 2015. PLoS Pathog 11(11): ev11.i11. https://doi.org/10.1371/image.ppat.v11.i11
Published: November 30, 2015
Copyright: © 2015 Talbot et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Mixed primary cultures from BALB/c mice brain infected with HCoV-OC43 (rOC/SG758R). Viral spreading was evaluated at 24 hours post-infection. Neurons were stained for microtubule-associated protein 2 (MAP2) (green) and the HCoV-OC43 S viral glycoprotein (red). Nuclei were stained in blue with DAPI. Magnification 200x.Talbot et al.
Image Credit: Talbot et al.