Death and population dynamics affect mutation rate estimates and evolvability under stress in bacteria
Fig 9
Segregation of a plasmid with inducible replication allows us to estimate death rate.
(a) Maintenance of the plasmid in presence of IPTG, (b) segregation of the plasmid in absence of IPTG, (c) computing population dynamics (death rate) from plasmid segregation in absence of IPTG. IPTG, Isopropyl β-D-1-thiogalactopyranoside.