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Simulation and Theory of Antibody Binding to Crowded Antigen-Covered Surfaces

Table 1

Best-fit values of the floating parameters in the theories for the flexible (flexible) and rigid (rigid) IgG molecules with excluded-volume interactions and for the flexible IgGs that are transparent to each other on the surface (ghost).

The theoretical models are Eq (8) (flexible and rigid) and the solution to Eq (14) (ghost). Indicated are also the free energy changes for the individual ligand-receptor binding steps obtained invoking at T = 300 K and assuming unit activity coefficients as in [32].

Table 1

doi: https://doi.org/10.1371/journal.pcbi.1004752.t001