High-Resolution Mapping Reveals Links of HP1 with Active and Inactive Chromatin Components
Figure 1
High-Resolution HP1-Binding Profiles
(A and B) Maps of Chromosome 2, (C) Chromosome 4, (D) pericentric light gene, (E) pericentric concertina gene, and (F) cytological region 31. Inset in (A) shows a more detailed view of the centromere-proximal 0.4 Mb of 2L. Each stick represents the mean HP1–Dam/Dam binding ratio of a single GATC fragment, for one representative experiment. Fragments significantly bound by HP1 are marked in red, fragments not significantly bound by HP1 are shown in black. Gaps originate from nonunique sequences for which binding cannot reliably be determined. Positions of genes (open rectangles) and TEs (gray rectangles) are shown in D–F. Arrows in (D) and (E) indicate orientation of the genes.
