Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss
Fig 2
GWAS results for post-noise exposure thresholds in the HMDP.
Manhattan plot showing the association (-log10) p-values (-logP) for 8 kHz in 64 HMDP inbred mouse strains. The analysis was performed using 108,064 SNPs with a minor allele frequency > 5%. Each chromosome is plotted on the x-axis in alternating brown and blue colors. SNPs on Chr. 2 and Chr. 17 for 8 kHz exceeded the predetermined genome-wide significance threshold (-logP = 5.39).
