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Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

Fig 3

Regional plot of the 8 kHz ABR post noise-exposure at Chr 17 association in the HMDP centered on the lead SNP at the Nox3 locus (rs33652818).

The blue diamond represents the most significant SNP (p = 9.63E-06) and SNPs are colored based on their LD with the most significant SNP being: red SNPs in LD at r2>0.8, orange SNPs in LD at r2>0.6 and green SNPs in LD at r2>0.4. The positions of all RefSeq genes are plotted using genome locations (NCBI’s Build37 genome assembly).

Fig 3

doi: https://doi.org/10.1371/journal.pgen.1005094.g003