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Antidiarrheal Efficacy and Cellular Mechanisms of a Thai Herbal Remedy

Figure 7

Herbal constituents responsible for the Cl channel inhibition activities of Krisanaklan.

A. Short-circuit current in T84 cells showing inhibition of forskolin (20 µM) and IBMX (100 µM)-stimulated CFTR Cl current by extracts from agarwood, Terminalia triptera, camphor and clove. B. Short-circuit current in T84 cells showing inhibition of ATP (100 µM)-stimulated CaCC Cl current by extracts. C. Short-circuit current in FRT-TMEM16A cells showing inhibition of Eact (10 µM)-stimulated TMEM16A Cl current by extracts. Data representative of 3 sets of experiments.

Figure 7

doi: https://doi.org/10.1371/journal.pntd.0002674.g007