Antidiarrheal Efficacy and Cellular Mechanisms of a Thai Herbal Remedy
Figure 7
Herbal constituents responsible for the Cl− channel inhibition activities of Krisanaklan.
A. Short-circuit current in T84 cells showing inhibition of forskolin (20 µM) and IBMX (100 µM)-stimulated CFTR Cl− current by extracts from agarwood, Terminalia triptera, camphor and clove. B. Short-circuit current in T84 cells showing inhibition of ATP (100 µM)-stimulated CaCC Cl− current by extracts. C. Short-circuit current in FRT-TMEM16A cells showing inhibition of Eact (10 µM)-stimulated TMEM16A Cl− current by extracts. Data representative of 3 sets of experiments.