Characterization of a dual-action adulticidal and larvicidal interfering RNA pesticide targeting the Shaker gene of multiple disease vector mosquitoes
Fig 1
Sh.463 siRNA has larvicidal and adulticidal activity in A. aegypti.
Significant larval mortality was observed after L1 larvae were soaked in 0.5 ug/ul Sh.463 siRNA (A). Significant adult mortality was observed after adult females were injected with 250 nl of 9 μg/μl Sh.463 siRNA (B). Data from Sh.463 vs. control siRNA-treated mosquitoes are represented here as mean percentage mortality; *** = P<0.001; error bars denote standard errors of the mean (SEM). The samples sizes for each treatment are noted on the columns in each graph in this figure and in all subsequent figures.
