Metnase Mediates Resistance to Topoisomerase II Inhibitors in Breast Cancer Cells
Figure 1
Topo IIα and Metnase interact in breast cancer cells.
(A) MCF 10A, MDA-MB-231, T-47D, and HCC1937 were analyzed by Western blot for expression of Topo IIα and Metnase protein expression. Actin is shown as a loading control. (B) Metnase and Topo IIα were immunoprecipitated from MDA-MB-231 cells and analyzed by Western blot.
