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Metabolite Profiling Uncovers Plasmid-Induced Cobalt Limitation under Methylotrophic Growth Conditions

Figure 2

Influence of cobalt concentration on growth.

Growth rates of M. extorquens AM1 strains observed during exponential growth on minimal medium with different cobalt concentrations. Values were determined for the wild-type strain (WT), strain AM1 with pCM80 plasmid coding for tetracycline resistance, and strain AM1 pCM160 plasmid coding for kanamycin resistance. Average values and standard deviations were calculated from three biological replicates carried out in shake flasks.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0007831.g002