Assembly of Linear Nano-Chains from Iron Oxide Nanospheres with Asymmetric Surface Chemistry
Figure 4
Theoretical and experimental analysis of the asymmetry on the nanosphere's surface chemistry.
(a) Schematic illustration of nanoparticle-resin surface binding. (b) Length of PEG polymers with respect to tether interactions as a function of repeating monomers per PEG molecule. The equilibrium distance is defined as the distance corresponding to the Flory radius of a polymer. The binding distance is defined as the length of polymer at which maximum resin-ligand complexes are formed. The fully extended length corresponds to the maximum length of a polymer tether. (c) Theoretical estimation of the partially modified area (PMA) as a function of nanoparticle size. (d) Experimental measurement (n = 3) of the portion of amines modified to thiols using NHS-functionalizedAlexa-488 to fluorescently tag the amines (* indicates p<0.05; data presented as mean ± standard deviation).
