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Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing

Figure 2

The m1045 mutant displays a complete loss of cell proliferation in all tissues at 4 dpf.

1-hour Edu incorporation (95–96 hfp) of unaffected siblings (A,C) and m1045 mutant embryos (B,D) in the transgenic ptf1∶GFP,ins:dsred background. Confocal projections of 4 dpf embryos of the pancreatic region (A,B) (lateral view) and of the head region (ventral view). Scale bars A,B 50 µm; C,D 100 µm. CMZ: ciliary marginal zone.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0034671.g002