Effects of Exposure to a DNA Damaging Agent on the Hypoxia Inducible Factors in Organogenesis Stage Mouse Limbs
Figure 6
Detection of hypoxia in limbs using Hypoxyprobe.
Hypoxyprobe™-1 reactivity was detected in the digit and core areas (Digit) of limbs where chondrogenesis occurs; staining in these areas was strong at 3 h and 6 h and diminished at 24 h. Hypoxyprobe reactivity was not observed in the interdigital regions (I.R.). No differences were observed between control and drug-treated limbs. Four separate replicates were done.
