Notch1 Is a 5-Fluorouracil Resistant and Poor Survival Marker in Human Esophagus Squamous Cell Carcinomas
Figure 5
Notch1 siRNA knockdown validation in KYSE70 cells (5A).
KYSE70 control means blank KYSE70 cells without any treatment. KYSE70 siRNA control means KYSE70 cells transfected with the non-specific siRNA. KYSE70 siRNA means KYSE70 cells transfected with the specific siRNA for Notch1. Notch1 siRNA knockdown in the KYSE70 cells significantly increases their 5-FU chemosensitivity both in normoxia (B) and hypoxia (C).
