Local Delivery of Polarized Macrophages Improves Reperfusion Recovery in a Mouse Hind Limb Ischemia Model
Figure 4
Reperfusion recovery after clodronate liposome treatment (n=9).
Reperfusion recovery is increased at day 14 in animals treated with either M1, M2a or M2c macrophages compared to NaCl treatment (***: p<0.001). Depletion of the circulating monocytes/macrophages did not inhibit reperfusion recovery and did not alter the effect of exogenously injected polarized macrophages.