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Local Delivery of Polarized Macrophages Improves Reperfusion Recovery in a Mouse Hind Limb Ischemia Model

Figure 5

Effect of inhibiting endogenous macrophage polarization (n=9).

Reperfusion recovery in IL10R1^fl/fl/LysMCre- (WT) and IL10R1^fl/fl/LysMCre+ (KO) mice. Treatment with M2c macrophages improves reperfusion recovery in IL10R1^fl/fl/LysMCre+ mice after 14 days compared to untreated animals (*: p<0.05).

doi: https://doi.org/10.1371/journal.pone.0068811.g005