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Single Nucleotide Polymorphism Network: A Combinatorial Paradigm for Risk Prediction

Figure 6

A network through which we represent the segregated pattern of combined genotypic data of case (acute coronary syndrome) and control population (healthy).

The 5 SNPs of each individual are combined to form super-set genotypes in both case and control. Thirty five unique genotype combinations are observed of which 14 combinations are specific to cases (marked as red), 7 combinations are specific to controls (marked as green) and 14 combinations are present in both case and control (marked as brown). The number of occurrences of each particular genotype combinations is illustrated through its corresponding edge-width.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0074067.g006