Pipoxolan Ameliorates Cerebral Ischemia via Inhibition of Neuronal Apoptosis and Intimal Hyperplasia through Attenuation of VSMC Migration and Modulation of Matrix Metalloproteinase-2/9 and Ras/MEK/ERK Signaling Pathways
Figure 5
Effects of PIPO on protein expression level in PDGF-BB-induced VSMCs.
The protein expression levels were determined by Western blot analysis. PIPO significantly decreased the expression levels of Ras, MEK, p-ERK, MMP-2, and MMP-9. **P<0.01, ***p<0.001 (n=6).
