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MiR-99a Antitumor Activity in Human Breast Cancer Cells through Targeting of mTOR Expression

Figure 1

Differential expression of miR-99a in human breast cancer tissues and cell lines.

(A) qRT-PCR analysis of miR-99a expression in 10 human breast cancer tissues vs. the distant non-tumor tissues. (B) qRT-PCR analysis of miR-99a expression in four human breast cancer cell lines and a normal human breast epithelial cell line. The level of miR-99a expression was normalized to U6 and compared to the normal cells. Data were normalized to U6 snRNA and represent the mean ± SD of three independent duplicate experiments. *, P<0.05 significant differences from HBL-100.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0092099.g001