Growth Inhibitory, Bactericidal, and Morphostructural Effects of Dehydrocostus Lactone from Magnolia sieboldii Leaves on Antibiotic-Susceptible and -Resistant Strains of Helicobacter pylori
Figure 4
Scanning electron micrographs.
The scanning electron micrographs for the H. pylori ATCC 700824 and five antibiotic-resistant strains of H. pylori treated without with dehydrocostus lactone (DCL) at the MIC showed conversion of the spiral to coccoid form, irrespective of antibiotic susceptibility of antibiotic-susceptible and -resistant strains. The coccoid-shaped cells were clustered and stuck to each other. Strains PED 503G, PED 3582GA, 221, H. pylori ATCC 43504, and B were resistant to amoxicillin, clarithromycin and tetracycline, metronidazole, metronidazole, and tetracycline and amoxicillin, respectively. Scale bar, 1 µm.
