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Evaluation of Global Differential Gene and Protein Expression in Primary Pterygium: S100A8 and S100A9 as Possible Drivers of a Signaling Network

Figure 5

Schematic showing how UV may trigger upstream molecular disturbances such as S100A8 and S100A9, ALDH3A1, and SERPINA2 which result in a cascade of events leading to pterygium progression.

↑represents up-regulation in pterygium compared to uninvolved conjunctiva, and ↓ represents down-regulation in pterygium.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0097402.g005