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Increased Cystic Fibrosis Transmembrane Conductance Regulators Expression and Decreased Epithelial Sodium Channel Alpha Subunits Expression in Early Abortion: Findings from a Mouse Model and Clinical Cases of Abortion

Figure 5

CFTR and ENaC-α protein detection by western blot analysis.

The expression of CFTR protein was stronger and the expression of ENaC-α protein was weaker in the decidua of CBA×DBA/2 mice compared to CBA×BALB/C mice (A). Moreover, the expression of CFTR protein was stronger and the expression of ENaC-α protein was weaker in the decidua of women who underwent a miscarriage than normal pregnant women (B). β-tubulin was used as the internal control (approximately 43 kD). Representative images are shown. Densitometry analysis data for CFTR and ENaC-α expression are normalized to the control (100%) for comparison. *P<0.05.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0099521.g005