The Effect of Tensile Stress on the Conformational Free Energy Landscape of Disulfide Bonds
Figure 1
Three models of increasing complexity used to investigate strained disulfide bonds.
(a) Diethyl disulfide (DEDS), (b) cystine, and the (c) polypeptide model (see text). The collinear constant force of magnitude is applied to the terminal methyl C atoms in panel a and to N and C termini in panels b and c. The dihedral angles
,
and
are defined in panel b.
