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Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells

Figure 4

Correlation between copy number and expression of the integrated cassette.

Mean fluorescence intensity (M.F.I.) of 62 GABEB clones positive for Venus expressing SB transposons are represented as circles; triangles indicate the M.F.I. of 70 GFP+ HaCaT clones transduced with a lentiviral vector (LV). Standard deviation bars are present for those clones carrying the same copy number. R2 coefficients of determination were extracted from the linear regression plot, green line for SA and T2 transposons and red line for LV.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0112712.g004