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Organization of Enzyme Concentration across the Metabolic Network in Cancer Cells

Fig 6

Analysis of enzyme concentrations in relation to kinetic and thermodynamic properties.

(a) Scatter plot of the log of the average KM and ΔG° value with each dot representing a different metabolic protein. (b) Scatter plot of the log of the average cell protein copy (CPC) and ΔG° values with each dot representing a different metabolic protein. (c) Scatter plot of the log of both the average KM and average CPC value with each dot representing a different metabolic protein. (d) Connectivity analysis of CPC, ΔG° and KM values for the various enzymes.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0117131.g006